Essential Oils Club

Manuka (Leptospermum scoparium)

Steam-distilledLeaves and twigsNew ZealandSeed to Seal quality

A gentle New Zealand relative of tea tree, prized in skin care for a softer aroma and soothing, everyday topical use.

How to use it

Safety. For topical use, dilute to 1–3% in a carrier oil and patch-test first, as with any new oil.
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In the diffuser

3–5 drops for a warm, grounding scent that suits the evening or a quiet background.

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On skin

Dilute to 1–3% in a carrier oil and patch-test — many find it gentler than tea tree.

Safety in detail

Max dermal use
Dilute in a carrier oil for skin
Phototoxic
No
  • A generally gentle oil; dilute before topical use as usual.
  • Not phototoxic. Keep out of reach of children.

Sources: Phytothérapie review (2010)

Composition & chemistry

Aggregated from 4 GC-MS samples across 4 peer-reviewed open-access studies (2020–2026). Figures are the distribution across those samples — median with interquartile range — not a single reading.

4 samples 4 papers 37 compounds 2020–2026 Moderate evidence base
  • Sesquiterpene hydrocarbon 54.6%
  • Oxygenated sesquiterpene 25.5%
  • Unclassified 11.7%
  • Other terpenoid/aromatic 6.4%
  • Monoterpene hydrocarbon 1.8%
ConstituentMedianTypical rangeMaxDetected in
cis-calamenene ↗ C15H22 21.6% 20.4–22.8% 24.0%
α-selinene ↗ C15H24 5.5% 3.8–7.7% 9.2%
α-cubebene ↗ C15H24 4.8% 3.4–6.2% 6.5%
δ-cadinene ↗ C15H24 4.3% 4.1–5.3% 6.4%
α-copaene ↗ C15H24 4.2% 4.1–4.6% 5.0%
β-selinene ↗ C15H24 3.9% 3.3–5.1% 8.4%
β-copaene ↗ C15H24 3.0% 1.6–4.5% 5.9%
γ-muurolene ↗ C15H24 1.7% 1.7–1.7% 1.7%
globulol ↗ C15H26O 1.4% 0.9–1.9% 2.4%
α-pinene ↗ C10H16 1.4% 1.1–1.7% 2.0%
cubenol ↗ C15H26O 1.3% 1.3–1.3% 1.3%
β-elemene ↗ C15H24 1.0% 1.0–1.0% 1.1%

+ 25 more compounds reported across the dataset.

4 peer-reviewed sources behind these figures
  1. Lee NH, Munkhtur E, Lee HS. (2026). Leptospermone acts as a predominantly non-competitive β-triketone inhibitor of tyrosinase. Scientific reports. Europe PMC ↗ · DOI · CC BY-NC-ND · 1 sample
  2. Bass NI, Parekh MY, Satyal P, Soni S, Jacob JA, Mack JP, Lobo DE. (2024). Manuka Essential Oil Triggers Apoptosis and Activation of c-Jun N-Terminal Kinase in Fibroblasts and Fibrosarcoma Cells. Molecules (Basel, Switzerland). Europe PMC ↗ · DOI · CC BY · 1 sample
  3. Pedonese F, Longo E, Torracca B, Najar B, Fratini F, Nuvoloni R. (2022). Antimicrobial and anti-biofilm activity of manuka essential oil against Listeria monocytogenes and Staphylococcus aureus of food origin. Italian journal of food safety. Europe PMC ↗ · DOI · CC BY-NC · 1 sample
  4. Muturi EJ, Selling GW, Doll KM, Hay WT, Ramirez JL. (2020). Leptospermum scoparium essential oil is a promising source of mosquito larvicide and its toxicity is enhanced by a biobased emulsifier. PloS one. Europe PMC ↗ · DOI · CC0 · 1 sample

Every figure above traces to a named table in one of these open-access papers. How this was built →

  • Leptospermone (β-triketones) — the signature manuka constituents; the focus of its antimicrobial research and a key marker of oil quality Phytothérapie review (2010)
Softer, sweeter and earthier than tea tree — closer to a forest-floor scent than a first-aid one.

What the research says

An honest read of the published research — what has actually been studied, at what stage. Not medical advice or a promise of results.

  • Manuka oil's β-triketones (leptospermone and relatives) have been studied for antimicrobial activity in the laboratory, sometimes compared with tea tree. These are in-vitro findings, not clinical proof of benefit.

    Phytothérapie review (2010)

Evidence & sources

Peer-reviewed research on Manuka's chemistry and safety. These describe composition and documented effects — not health or treatment claims.

  1. High-grade manuka oil is distinguished by its β-triketone content (leptospermone), the constituents most associated with its studied antimicrobial activity.

    Phytothérapie review (2010)

Frequently asked questions

Is manuka oil the same as manuka honey?

They come from the same plant but are different products. Manuka honey's activity is tied to methylglyoxal; the essential oil's activity is tied to its β-triketones. Don't assume claims about one apply to the other. Phytothérapie review (2010)

How is manuka different from tea tree?

Both are Australasian Myrtaceae oils studied for antimicrobial activity, but they're chemically different — tea tree is terpinen-4-ol-driven, manuka is triketone/sesquiterpene-driven. Manuka is often described as gentler-smelling. Phytothérapie review (2010)

Is manuka oil phototoxic?

No — manuka isn't phototoxic, so there's no sun-exposure restriction. Just dilute it for skin use as usual.

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